Protein A Resin Market Is Expected To Reach USD 1.9 Billion By 2025, At A CAGR Of 11.4%

The growth in this market is mainly driven by the growing demand for disposable pre-packed columns, increasing demand for therapeutic antibodies, and the increasing pharmaceutical R&D spending are expected to drive the growth of this market during the forecast period. However, the high cost of resins is expected to limit the growth of this market.

What the Market Looks Like?

The protein A resin market is expected to reach USD 1.9 billion by 2025 from USD 1.1 billion in 2020, at a CAGR of 11.4% during the forecast period.  North America is expected to dominate the protein A resin market during the forecast period.

Protein A resins cost around 5-10 times more than other types of resins. Though there are no alternative techniques that can achieve purification levels as high as protein A resins, their high cost makes end users look for alternatives. Some of the techniques that provide acceptable levels of purification include both chromatography and non-chromatography methods. mAb crystallization and precipitation by polyethylene glycol (PEG) precipitation are being explored as alternatives for protein A chromatography.

COVID-19 Impact on the Protein A Resin Market : 

For the past 30 years, monoclonal antibodies have transformed the way we treat various diseases—they have proven to be more effective, better tolerated, and easier to deliver than other treatments. Researchers are optimistic that monoclonal antibodies could help prevent and treat early infections of COVID-19. Several monoclonal antibodies that are licensed or in development for other diseases are in clinical trials for COVID-19. One of these is adalimumab, used to treat arthritis and Crohn’s disease; the University of Oxford recently launched a trial to look at its potential to treat people in care homes, funded by the COVID-19 Therapeutics Accelerator.

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What are Key Trends in the Market?

The growth of the Protein A Resin Market is primarily influenced by the following factors:

  • Growing demand for disposable pre-packed columns
  • Increasing demand for therapeutic antibodies
  • Increasing pharmaceutical R&D spending
  • High cost of resins
  • Dearth of skilled professionals

An increasing number of CMOs and CROs are offering their services to pharmaceutical companies across the globe. This is expected to offer potential growth opportunities to protein A resin manufacturers during the forecast period.

Based on end user, the protein A resin market is segmented into pharmaceutical & biopharmaceutical companies, academic research institutes, and other end users. In 2020, the pharmaceutical and biopharmaceutical companies segment is expected to command the largest share of the protein A resin market. The increasing R&D expenditure of pharmaceutical and biopharmaceutical companies is the major factor driving the growth of this end-user segment.

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North America is expected to dominate the protein A resin market during the forecast period

Geographically, North America is expected to dominate the global the protein A resin market in 2019, while the Asia Pacific region is expected to register the highest CAGR during the forecast period. The high growth in this region can be attributed to the increased R&D activities, as APAC has emerged as a key pharmaceutical and biopharmaceutical research hub. Considering this, a number of key pharmaceutical and biopharmaceutical companies have set up their research centers in the region.